• 250
  • 350
  • Great Deal
  • Low Mileage
  • Automatic
  • Sedan
  • Handsfree/Bluetooth Integration
  • White
  • RWD
  • Black
  • Well-Equipped
  • Keyless Ignition
  • AWD
  • iPod Adapter
  • Convertible
  • One Owner
  • Gray
  • Heated Seats
  • 2014
  • Leather Trimmed Interior
  • Silver
  • 2010
  • 2015
  • CD (Single Disc)
  • 2012
  • 2011
  • Lower Than Average Mileage
  • 2007
  • 2013
  • Good Deal
  • 2008
  • Blue
  • Red

Price Range

$0 $60,000+

Max Mileage

New $80,000+

MPG

Min 14 Max 50

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22 Results for

Used Lexus IS For Sale in Roanoke, VA

Search Results

Photo 1:  2011 Lexus IS 350 Base in Roanoke, VA exterior view from front driver's side
Photo 2: interior dashboard and console 2011 Lexus IS 350 Base in Roanoke, VA
Photo 3:  2011 Lexus IS 350 Base in Roanoke, VA exterior view from rear passenger side

Automatic / RWD / 6 Cyl
20 mpg city / 27 mpg hwy

  • Dealer Page
  • Call
  • Get Directions
$20,990

2011 Lexus IS 350 Base

45,074 miles / Roanoke, VA

Photo 1: Ultra White 2014 Lexus IS 350 Base in Roanoke, VA
Photo 2: Ultra White 2014 Lexus IS 350 Base in Roanoke, VA front view of grill, headlights, hood and windshield
Photo 3: Ultra White 2014 Lexus IS 350 Base in Roanoke, VA exterior view of driver's side
Photo 4: Ultra White 2014 Lexus IS 350 Base in Roanoke, VA exterior view from rear passenger side
Photo 5: Ultra White 2014 Lexus IS 350 Base in Roanoke, VA view of rear bumper

Automatic / AWD / 6 Cyl
19 mpg city / 26 mpg hwy

  • Dealer Page
  • Call
  • Get Directions
$30,957

2014 Lexus IS 350 Base

25,497 miles / Roanoke, VA

Photo 1: Smoky Granite Mica 2010 Lexus IS 250 in Roanoke, VA exterior view from front driver's side
Photo 2: Smoky Granite Mica 2010 Lexus IS 250 in Roanoke, VA
Photo 3: cockpit view from driver’s seat 2010 Lexus IS 250 in Roanoke, VA
Photo 4: interior dashboard and console 2010 Lexus IS 250 in Roanoke, VA
Photo 5: Smoky Granite Mica 2010 Lexus IS 250 in Roanoke, VA exterior view of passenger side

Automatic / AWD / 6 Cyl
20 mpg city / 26 mpg hwy

  • Get Directions
$16,495

2010 Lexus IS 250

58,343 miles / Roanoke, VA

Photo 1:  2014 Lexus IS 250 in Roanoke, VA exterior view from front driver's side
Photo 2:  2014 Lexus IS 250 in Roanoke, VA
Photo 3: cockpit view from driver’s seat 2014 Lexus IS 250 in Roanoke, VA
Photo 4: interior dashboard and console 2014 Lexus IS 250 in Roanoke, VA
Photo 5:  2014 Lexus IS 250 in Roanoke, VA exterior view from rear driver's side

Automatic / AWD / 6 Cyl
20 mpg city / 27 mpg hwy

  • Call Dealer
  • Get Directions
$27,531

2014 Lexus IS 250

31,559 miles / Roanoke, VA

Photo 1: Obsidian 2014 Lexus IS 250 in Lynchburg, VA exterior view from front driver's side
Photo 2: Obsidian 2014 Lexus IS 250 in Lynchburg, VA
Photo 3: cockpit view from driver’s seat 2014 Lexus IS 250 in Lynchburg, VA
Photo 4: Obsidian 2014 Lexus IS 250 in Lynchburg, VA front view of grill, headlights, hood and windshield
Photo 5: Obsidian 2014 Lexus IS 250 in Lynchburg, VA view of rear bumper

Automatic / RWD / 6 Cyl
21 mpg city / 30 mpg hwy

  • Call Dealer
  • Get Directions
$24,645

2014 Lexus IS 250

21,426 miles / Lynchburg, VA

Photo 1: interior dashboard and console 2015 Lexus IS 250 in Roanoke, VA
Photo 2: Atomic Silver 2015 Lexus IS 250 in Roanoke, VA exterior view of passenger side
Photo 3: Atomic Silver 2015 Lexus IS 250 in Roanoke, VA closeup view of wheel
Photo 4: Atomic Silver 2015 Lexus IS 250 in Roanoke, VA exterior view from rear passenger side
Photo 5: 2015 Lexus IS 250 with  in Roanoke, VA

Automatic / RWD / 6 Cyl
21 mpg city / 30 mpg hwy

  • Call Dealer
  • Get Directions
Not Priced

2015 Lexus IS 250

17,348 miles / Roanoke, VA

Photo 1: Matador Red Mica 2010 Lexus IS 250 in Roanoke, VA
Photo 2: interior dashboard and console 2010 Lexus IS 250 in Roanoke, VA
Photo 3: Matador Red Mica 2010 Lexus IS 250 in Roanoke, VA exterior view from rear driver's side
Photo 4: Matador Red Mica 2010 Lexus IS 250 in Roanoke, VA view of rear bumper
Photo 5: Matador Red Mica 2010 Lexus IS 250 in Roanoke, VA exterior view from rear passenger side

Automatic / RWD / 6 Cyl
21 mpg city / 29 mpg hwy

  • Call Dealer
  • Get Directions
Not Priced

2010 Lexus IS 250

89,984 miles / Roanoke, VA

Photo 1: Starfire Pearl 2014 Lexus IS 350 in Roanoke, VA exterior view from front driver's side
Photo 2: Starfire Pearl 2014 Lexus IS 350 in Roanoke, VA closeup view of wheel
Photo 3: Starfire Pearl 2014 Lexus IS 350 in Roanoke, VA exterior view from rear passenger side
Photo 4: Starfire Pearl 2014 Lexus IS 350 in Roanoke, VA view of rear bumper
Photo 5: Starfire Pearl 2014 Lexus IS 350 in Roanoke, VA exterior view of passenger side

Automatic / RWD / 6 Cyl
19 mpg city / 27 mpg hwy

  • Call Dealer
  • Get Directions
Not Priced

2014 Lexus IS 350

9,364 miles / Roanoke, VA

Photo 1: Obsidian 2015 Lexus IS 250 in Roanoke, VA exterior view from front driver's side
Photo 2: interior dashboard and console 2015 Lexus IS 250 in Roanoke, VA
Photo 3: Obsidian 2015 Lexus IS 250 in Roanoke, VA closeup view of wheel
Photo 4: Obsidian 2015 Lexus IS 250 in Roanoke, VA exterior view from rear passenger side
Photo 5: 2015 Lexus IS 250 with  in Roanoke, VA

Automatic / AWD / 6 Cyl
20 mpg city / 27 mpg hwy

  • Call Dealer
  • Get Directions
Not Priced

2015 Lexus IS 250

10,528 miles / Roanoke, VA

Photo 1: Starfire Pearl 2010 Lexus IS 250 in Roanoke, VA
Photo 2: interior dashboard and console 2010 Lexus IS 250 in Roanoke, VA
Photo 3: Starfire Pearl 2010 Lexus IS 250 in Roanoke, VA closeup view of wheel
Photo 4: Starfire Pearl 2010 Lexus IS 250 in Roanoke, VA exterior view from rear driver's side
Photo 5: interior dashboard and console 2010 Lexus IS 250 in Roanoke, VA

Automatic / RWD / 6 Cyl
21 mpg city / 29 mpg hwy

  • Call Dealer
  • Get Directions
Not Priced

2010 Lexus IS 250

26,273 miles / Roanoke, VA

Photo 1: Obsidian 2007 Lexus IS 250 in Roanoke, VA exterior view from front driver's side
Photo 2: interior dashboard and console 2007 Lexus IS 250 in Roanoke, VA
Photo 3: Obsidian 2007 Lexus IS 250 in Roanoke, VA closeup view of wheel
Photo 4: Obsidian 2007 Lexus IS 250 in Roanoke, VA exterior view from rear passenger side
Photo 5: 2007 Lexus IS 250 with  in Roanoke, VA

Automatic / AWD / 6 Cyl
20 mpg city / 26 mpg hwy

  • Call Dealer
  • Get Directions
Not Priced

2007 Lexus IS 250

74,806 miles / Roanoke, VA

Photo 1: 2012 Lexus IS 250 with  in Lynchburg, VA

RWD / 6 Cyl
21 mpg city / 29 mpg hwy

$29,997

2012 Lexus IS 250

15,665 miles / Lynchburg, VA

Photo 1: 2014 Lexus IS 250 Base with  in Roanoke, VA

Automatic / AWD / 6 Cyl
20 mpg city / 27 mpg hwy

Not Priced

2014 Lexus IS 250 Base

9,825 miles / Roanoke, VA

Photo 1: 2015 Lexus IS 350 Base in Lynchburg, VA

Automatic / RWD / 6 Cyl
19 mpg city / 27 mpg hwy

Not Priced

2015 Lexus IS 350 Base

19,223 miles / Lynchburg, VA

Photo 1: 2015 Lexus IS 250 Base with  in Roanoke, VA

Automatic / RWD / 6 Cyl
21 mpg city / 30 mpg hwy

Not Priced

2015 Lexus IS 250 Base

3,092 miles / Roanoke, VA

Photo 1: 2013 Lexus IS 250 Base with  in Roanoke, VA

Automatic / RWD / 6 Cyl
21 mpg city / 29 mpg hwy

Not Priced

2013 Lexus IS 250 Base

26,633 miles / Roanoke, VA

Photo 1: 2012 Lexus IS 350 Base with  in Roanoke, VA

Automatic / AWD / 6 Cyl
18 mpg city / 25 mpg hwy

Not Priced

2012 Lexus IS 350 Base

34,849 miles / Roanoke, VA

Photo 1: 2013 Lexus IS 250 Base in Lynchburg, VA

Automatic / RWD / 6 Cyl
21 mpg city / 29 mpg hwy

Not Priced

2013 Lexus IS 250 Base

25,419 miles / Lynchburg, VA

Photo 1: 2010 Lexus IS 250 Base with  in Roanoke, VA

Automatic / AWD / 6 Cyl
20 mpg city / 26 mpg hwy

Not Priced

2010 Lexus IS 250 Base

78,291 miles / Roanoke, VA

Photo 1: 2011 Lexus IS 250 Base with  in Roanoke, VA

Automatic / RWD / 6 Cyl
21 mpg city / 29 mpg hwy

Not Priced

2011 Lexus IS 250 Base

11,451 miles / Roanoke, VA

Automatic / AWD / 6 Cyl
20 mpg city / 26 mpg hwy

$9,995

2008 Lexus IS 250 Base

137,325 miles / Danville, VA

Automatic / AWD / 6 Cyl
20 mpg city / 26 mpg hwy

$6,995

2007 Lexus IS 250 Base

111,302 miles / Roanoke, VA