• Denali
  • SLT
  • SLE
  • Base
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  • Work Truck
  • Great Deal
  • 4WD
  • Navigation System
  • Automatic
  • Well-Equipped
  • Diesel
  • White
  • Heated Seats
  • Black
  • Satellite Radio
  • 2015
  • Remote Start
  • Gasoline
  • Flexible-Fuel
  • Low Mileage
  • Keyless Entry
  • Good Deal
  • 2016
  • 2014
  • MP3
  • Handsfree/Bluetooth Integration
  • Red
  • 2012
  • 2011
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  • Gray
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  • 2005
  • 2013
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  • 2017
  • Fair Price
  • RWD
  • Lower Than Average Mileage
  • 2007
  • Certified Pre-Owned
  • Popular Model
  • 2009
  • 2010
  • Beige
  • 2008
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  • Going Fast
  • 2004
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Price Range

$0 $60,000+

Max Mileage

New $80,000+

MPG

Min 14 Max 50

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47 Results for

Used GMC Sierra 2500HD For Sale in Des Moines, IA

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Photo 1:  2014 GMC Sierra 2500HD Denali in Urbandale, IA exterior view from front driver's side
Photo 2:  2014 GMC Sierra 2500HD Denali in Urbandale, IA
Photo 3:  2014 GMC Sierra 2500HD Denali in Urbandale, IA exterior view of driver's side
Photo 4:  2014 GMC Sierra 2500HD Denali in Urbandale, IA exterior view of passenger side
Photo 5:  2014 GMC Sierra 2500HD Denali in Urbandale, IA exterior view from rear driver's side

Automatic / 4WD / 8 Cyl

  • Get Directions
$44,894

2014 GMC Sierra 2500HD Denali

62,332 miles Urbandale, IA

Photo 1:  2011 GMC Sierra 2500HD Denali in Des Moines, IA exterior view from front driver's side
Photo 2: cockpit view from driver’s seat 2011 GMC Sierra 2500HD Denali in Des Moines, IA
Photo 3: 2011 GMC Sierra 2500HD Denali with  in Des Moines, IA
Photo 4:  2011 GMC Sierra 2500HD Denali in Des Moines, IA front view of grill, headlights, hood and windshield
Photo 5: 2011 GMC Sierra 2500HD Denali with  in Des Moines, IA

Automatic / 4WD / 8 Cyl

  • Get Directions
$30,330

2011 GMC Sierra 2500HD Denali

94,175 miles Des Moines, IA

Photo 1: Summit White 2017 GMC Sierra 2500HD Denali in Ankeny, IA exterior view from front driver's side
Photo 2: Summit White 2017 GMC Sierra 2500HD Denali in Ankeny, IA
Photo 3: interior dashboard and console 2017 GMC Sierra 2500HD Denali in Ankeny, IA
Photo 4: cockpit view from driver’s seat 2017 GMC Sierra 2500HD Denali in Ankeny, IA
Photo 5: 2017 GMC Sierra 2500HD Denali with  in Ankeny, IA

Automatic / 4WD / 8 Cyl

  • Get Directions
$56,515

2017 GMC Sierra 2500HD Denali

21,750 miles Ankeny, IA

Photo 1:  2010 GMC Sierra 2500HD SLT in Des Moines, IA exterior view from front driver's side

Automatic / 4WD / 8 Cyl

  • Get Directions
$20,995

2010 GMC Sierra 2500HD SLT

162,427 miles Des Moines, IA

Photo 1:  2013 GMC Sierra 2500HD SLE in Ankeny, IA exterior view from front driver's side
Photo 2:  2013 GMC Sierra 2500HD SLE in Ankeny, IA
Photo 3: interior dashboard and console 2013 GMC Sierra 2500HD SLE in Ankeny, IA
Photo 4: cockpit view from driver’s seat 2013 GMC Sierra 2500HD SLE in Ankeny, IA
Photo 5: 2013 GMC Sierra 2500HD SLE with  in Ankeny, IA

Automatic / 4WD / 8 Cyl

  • Get Directions
$34,048

2013 GMC Sierra 2500HD SLE

26,502 miles Ankeny, IA

Photo 1: 2015 GMC Sierra 2500HD SLT with  in Ankeny, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$48,300

2015 GMC Sierra 2500HD SLT

51,050 miles Ankeny, IA

Photo 1: Onyx Black 2013 GMC Sierra 2500HD SLT in Grinnell, IA
Photo 2: interior dashboard and console 2013 GMC Sierra 2500HD SLT in Grinnell, IA
Photo 3: 2013 GMC Sierra 2500HD SLT with  in Grinnell, IA
Photo 4: Onyx Black 2013 GMC Sierra 2500HD SLT in Grinnell, IA front view of grill, headlights, hood and windshield
Photo 5: 2013 GMC Sierra 2500HD SLT with  in Grinnell, IA

Automatic / 4WD / 8 Cyl

  • Get Directions
$43,537

2013 GMC Sierra 2500HD SLT

48,164 miles Grinnell, IA

Photo 1: 2013 GMC Sierra 2500HD Denali with  in Ankeny, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$50,700

2013 GMC Sierra 2500HD Denali

15,143 miles Ankeny, IA

Photo 1: Doeskin Tan 2004 GMC Sierra 2500HD SLE in Urbandale, IA exterior view from front driver's side
Photo 2: Doeskin Tan 2004 GMC Sierra 2500HD SLE in Urbandale, IA
Photo 3: interior dashboard and console 2004 GMC Sierra 2500HD SLE in Urbandale, IA
Photo 4: 2004 GMC Sierra 2500HD SLE with  in Urbandale, IA
Photo 5: Doeskin Tan 2004 GMC Sierra 2500HD SLE in Urbandale, IA front view of grill, headlights, hood and windshield

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$16,989

2004 GMC Sierra 2500HD SLE

103,012 miles Urbandale, IA

Photo 1: Cardinal Red 2016 GMC Sierra 2500HD SLT in Norwalk, IA exterior view from front driver's side
Photo 2: Cardinal Red 2016 GMC Sierra 2500HD SLT in Norwalk, IA
Photo 3: interior dashboard and console 2016 GMC Sierra 2500HD SLT in Norwalk, IA
Photo 4: cockpit view from driver’s seat 2016 GMC Sierra 2500HD SLT in Norwalk, IA
Photo 5: 2016 GMC Sierra 2500HD SLT with  in Norwalk, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$53,000

2016 GMC Sierra 2500HD SLT

14,201 miles Norwalk, IA

Photo 1:  2016 GMC Sierra 2500HD Denali in Clive, IA exterior view from front driver's side
Photo 2:  2016 GMC Sierra 2500HD Denali in Clive, IA
Photo 3: interior dashboard and console 2016 GMC Sierra 2500HD Denali in Clive, IA
Photo 4:  2016 GMC Sierra 2500HD Denali in Clive, IA front view of grill, headlights, hood and windshield
Photo 5: 2016 GMC Sierra 2500HD Denali with  in Clive, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$59,969

2016 GMC Sierra 2500HD Denali

35,148 miles Clive, IA

Photo 1: 2016 GMC Sierra 2500HD Denali with  in Ankeny, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$47,900

2016 GMC Sierra 2500HD Denali

27,964 miles Ankeny, IA

Photo 1:  2008 GMC Sierra 2500HD in Des Moines, IA exterior view from front driver's side
Photo 2:  2008 GMC Sierra 2500HD in Des Moines, IA
Photo 3: interior dashboard and console 2008 GMC Sierra 2500HD in Des Moines, IA
Photo 4: 2008 GMC Sierra 2500HD with  in Des Moines, IA
Photo 5:  2008 GMC Sierra 2500HD in Des Moines, IA front view of grill, headlights, hood and windshield

Automatic / RWD / 8 Cyl

  • Call Dealer
  • Get Directions
$23,950

2008 GMC Sierra 2500HD

71,793 miles Des Moines, IA

Photo 1: Onyx Black 2014 GMC Sierra 2500HD SLT in Ankeny, IA exterior view from front driver's side
Photo 2: Onyx Black 2014 GMC Sierra 2500HD SLT in Ankeny, IA
Photo 3: 2014 GMC Sierra 2500HD SLT with  in Ankeny, IA
Photo 4: Onyx Black 2014 GMC Sierra 2500HD SLT in Ankeny, IA exterior view from rear driver's side
Photo 5: Onyx Black 2014 GMC Sierra 2500HD SLT in Ankeny, IA exterior view from rear passenger side

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$42,900

2014 GMC Sierra 2500HD SLT

34,503 miles Ankeny, IA

Photo 1:  2015 GMC Sierra 2500HD Denali in Clive, IA exterior view from front driver's side
Photo 2:  2015 GMC Sierra 2500HD Denali in Clive, IA
Photo 3: interior dashboard and console 2015 GMC Sierra 2500HD Denali in Clive, IA
Photo 4:  2015 GMC Sierra 2500HD Denali in Clive, IA front view of grill, headlights, hood and windshield
Photo 5: 2015 GMC Sierra 2500HD Denali with  in Clive, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$54,469

2015 GMC Sierra 2500HD Denali

68,005 miles Clive, IA

Photo 1: Summit White 2016 GMC Sierra 2500HD Base in Urbandale, IA exterior view from front driver's side
Photo 2: Summit White 2016 GMC Sierra 2500HD Base in Urbandale, IA
Photo 3: interior dashboard and console 2016 GMC Sierra 2500HD Base in Urbandale, IA
Photo 4: cockpit view from driver’s seat 2016 GMC Sierra 2500HD Base in Urbandale, IA
Photo 5: 2016 GMC Sierra 2500HD Base in Urbandale, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$27,989

2016 GMC Sierra 2500HD Base

25,466 miles Urbandale, IA

Photo 1: Summit White 2016 GMC Sierra 2500HD Base in Urbandale, IA exterior view from front driver's side
Photo 2: Summit White 2016 GMC Sierra 2500HD Base in Urbandale, IA
Photo 3: cockpit view from driver’s seat 2016 GMC Sierra 2500HD Base in Urbandale, IA
Photo 4: 2016 GMC Sierra 2500HD Base in Urbandale, IA
Photo 5: Summit White 2016 GMC Sierra 2500HD Base in Urbandale, IA front view of grill, headlights, hood and windshield

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$28,489

2016 GMC Sierra 2500HD Base

23,785 miles Urbandale, IA

Photo 1:  2011 GMC Sierra 2500HD SLE in Des Moines, IA exterior view from front driver's side
Photo 2:  2011 GMC Sierra 2500HD SLE in Des Moines, IA
Photo 3: interior dashboard and console 2011 GMC Sierra 2500HD SLE in Des Moines, IA
Photo 4: 2011 GMC Sierra 2500HD SLE with  in Des Moines, IA
Photo 5:  2011 GMC Sierra 2500HD SLE in Des Moines, IA exterior view of driver's side

Automatic / 4WD / 8 Cyl

  • Get Directions
$29,995

2011 GMC Sierra 2500HD SLE

123,512 miles Des Moines, IA

Photo 1:  2015 GMC Sierra 2500HD Denali in Clive, IA exterior view from front driver's side
Photo 2: interior dashboard and console 2015 GMC Sierra 2500HD Denali in Clive, IA
Photo 3:  2015 GMC Sierra 2500HD Denali in Clive, IA front view of grill, headlights, hood and windshield
Photo 4: 2015 GMC Sierra 2500HD Denali with  in Clive, IA
Photo 5: 2015 GMC Sierra 2500HD Denali with  in Clive, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$51,969

2015 GMC Sierra 2500HD Denali

52,449 miles Clive, IA

Photo 1:  2012 GMC Sierra 2500HD Work Truck in Des Moines, IA
Photo 2: interior dashboard and console 2012 GMC Sierra 2500HD Work Truck in Des Moines, IA
Photo 3: cockpit view from driver’s seat 2012 GMC Sierra 2500HD Work Truck in Des Moines, IA
Photo 4: 2012 GMC Sierra 2500HD Work Truck with  in Des Moines, IA
Photo 5:  2012 GMC Sierra 2500HD Work Truck in Des Moines, IA front view of grill, headlights, hood and windshield

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$26,990

2012 GMC Sierra 2500HD Work Truck

98,689 miles Des Moines, IA

Automatic / 4WD / 8 Cyl

  • Call Dealer
  • Get Directions
$50,500

2016 GMC Sierra 2500HD Denali

52,585 miles Pella, IA

Photo 1:  2012 GMC Sierra 2500HD Denali in Des Moines, IA exterior view from front driver's side
Photo 2:  2012 GMC Sierra 2500HD Denali in Des Moines, IA
Photo 3: interior dashboard and console 2012 GMC Sierra 2500HD Denali in Des Moines, IA
Photo 4: 2012 GMC Sierra 2500HD Denali with  in Des Moines, IA
Photo 5:  2012 GMC Sierra 2500HD Denali in Des Moines, IA exterior view from rear driver's side

Automatic / 4WD / 8 Cyl

$28,995

2012 GMC Sierra 2500HD Denali

173,788 miles Des Moines, IA

Photo 1: 2015 GMC Sierra 2500HD SLT with  in IA

Automatic / 4WD / 8 Cyl

$41,495

2015 GMC Sierra 2500HD SLT

62,815 miles IA

Photo 1: 2012 GMC Sierra 2500HD SLE with  in IA

Automatic / 4WD / 8 Cyl

$28,995

2012 GMC Sierra 2500HD SLE

86,248 miles IA